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Zymox Topical Hot Spot Spray for Dogs and Cats with 1% Hydrocortisone

Zymox Topical Hot Spot Spray for Dogs and Cats with 1% Hydrocortisone is my go-to treatment for any severely inflamed localized skin problem.  It treats bacterial and fungal infections without harsh antibiotics or antifungals and provides instant relief from inflammation and pain.

$17.00

Description

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From the brand

  • Spray for dogs and cats; veterinarian-strength with 1% Hydrocortisone
  • For relief, apply directly to the skin; no need for pre-cleaning
  • Soothing no-sting formula for pet wound care and skin infections caused by germs, fungi, and yeast P
  • atented LP3 Enzyme System for relief from itchy, infected or irritated skin plus soothing aloe vera
  • Non-toxic, safe, and gentle if your pet licks the application site; promotes healthy skin

Support for the use of Zymox Spray

https://www.zymox.com/wp-content/uploads/2019/12/PetKingBrandsVeterinarian.pdf

 

Our anti-itch spray for dogs and cats also soothes skin wounds and infections. The no-sting formula with the ZYMOX patented LP3 Enzyme System aids recovery from skin infections caused by germs, fungi and yeast.

ZYMOX Spray is Ideal for use on:

  • Skin bumps and pustules
  • Red, irritated or inflamed skin
  • Itchy skin
  • Red, discolored paws, irritated by licking
  • Red, bald patches, often irritated by licking
  • Wounds and cuts
  • Infected skin
  • Hot spots

ZYMOX Spray is simple to use – spray onto the affected area once or twice a day, for up to seven days.

Because ZYMOX hot spot spray for dogs and cats only contains safe, gentle and non-toxic ingredients, it’s safe if your inquisitive pet licks the application site.

LP3 Enzyme System

Recurrent skin infections, hot spots and irritation can lead to a distressed pet and repeat visits to your veterinarian. They can also mean repeat courses of medication, which can lead to problems with resistant bugs that don’t respond to conventional medicinal treatment.

The ZYMOX patented LP3 Enzyme System is effective on a broad spectrum of germs, fungi and yeast that cause skin problems.

Enzymes are naturally-occurring proteins, and the LP3 Enzyme System from ZYMOX helps destroy microorganisms without attacking healthy cells or irritating the skin. Enzymes don’t develop a resistance to microbes and will continue to work for your pet when they need them.

There’s no need to pre-clean sore areas first. Simply spray without cleaning. The enzymes react with organic matter within the skin helping to manage infections and hot spots.

 

Veterinarian-Strength 1% Hydrocortisone and Hydrocortisone-Free Formulas

Patented Antimicrobial LP3 Enzyme System

Simple to Use with No Painful Pre-Cleaning

ZYMOX Topical Spray includes 1% Hydrocortisone for relief from itching and inflammation.

ZYMOX Topical Spray is also available without Hydrocortisone for sensitive animals, rodents, exotics, pets sensitive to Hydrocortisone and pets that are pregnant or lactating.

ZYMOX Topical Spray is an all-in-one solution for infections caused by germs, fungi and yeast.

Enzymes do not develop a resistance to microbes, so this spray will continue to work for your pet.

The LP3 Enzyme System reacts with biological materials in the skin to form its powerful soothing properties.

Simple, effective relief.

Apply once or twice a day by spraying the entire affected area.

There’s no need to cause fear or upset in your pet, as there’s no painful pre-cleaning necessary.

Pre-cleaning and cleaning during use disrupts the biological system and will negatively affect results.

 
 

Additional information

Is Discontinued By Manufacturer ‏ : ‎

No

Package Dimensions ‏ : ‎

5.63 x 1.85 x 1.38 inches; 2 ounces

Date First Available ‏ : ‎

July 20, 2011

Manufacturer ‏ : ‎

Pet King Brands

ASIN ‏ : ‎

B000RI3E5I

Customer Reviews:

1,672 ratings

60 reviews for Zymox Topical Hot Spot Spray for Dogs and Cats with 1% Hydrocortisone

  1. Chasta S

    5.0 out of 5 stars

    Works Really Well!

    This really helped my cat to stop overgrooming. After I apply, it lasts all day and she doesn’t try to remove it so, it’s clearly giving her relief from the itching. I’m really glad to have found this because it actually works unlike countless other brands I’ve tried. While the container is small, it does not take much to work and so it lasts quite a while.

    One person found this helpful

  2. Dreamer2011

    5.0 out of 5 stars

    Was a gift and arrived on time

    Was a gift and works great!

  3. Missy

    5.0 out of 5 stars

    Zymox is a magical spray

    I’ve used Zymox on three of my dogs. It is great for stopping anything itchy or possibly irritating. A spray or two and the itch goes away. Yes, that fast, it goes away! It can keep you from having to deal with an infected hot spot down the road since your dog will not have the desire to lick or chew or scratch after spraying. I call it a magical spray – it works So Good!

    One person found this helpful

  4. BCO

    4.0 out of 5 stars

    Seems to work fine.

    Easy to use…could work better if the spray sound didn’t scare my cat but that isn’t the products fault. Maybe, she’ll get over it. In the meantime, I spray on my fingers and apply to the cat.

    3 people found this helpful

  5. Lily

    5.0 out of 5 stars

    Miracle worker!

    My Persian cat ripped her hair off after coming in contact with grass, we were prescribed medications from the vet, wrapped her wounds nothing would work. I bought this as a last effort as its the same brand we use for my Shih Tzu’s ears. Within days you could already see improvement!!

  6. V Jones

    5.0 out of 5 stars

    A good OTC help for itchy pup

    I bought this for my 50 pound dog to spray on the webs of her feet. She has grass allergies and constantly licks and chews on her feet. This spray did offer temporary relief for her. It shouldn’t replace seeing a vet for extreme cases but does help on the really itchy days. I would buy this again.

    3 people found this helpful

  7. Springlering

    5.0 out of 5 stars

    Cat Approved

    Got this to help with an itchy rash on an indoor cat. She was suffering terribly. She was scared of the sprayer at first, but within a day or two she recognized it was giving relief and actually ponied up for a squirt and a nice rub through her fur. Worked very well.Also tried spraying it on her brush and brushing it through her fur. She liked that as well.Did leave her with sort of temporary unsightly yucky fur, but WELL worth the relief it provided and her fur was back to normal within a day or two.

    3 people found this helpful

  8. Amazon Customer

    5.0 out of 5 stars

    It works

    This is a life saver when my dog licks it scratches in one spot. It is so nice to know that I can give her relief just from one spray.

  9. mel_13.1

    5.0 out of 5 stars

    Works the first time

    Leave on the five minutes as instructed and use twice weekly. Totally works shampoo leave on conditioner for sure with the spray after 100% works. If you love your furry family member like I do mine and can’t stand to see them suffer BUY this Use all three together and peace is delivered after only the first use🐾

    One person found this helpful

  10. Angie M.

    5.0 out of 5 stars

    It’s good

    Some products work on some dogs and not others. It’s a good spray, it did help our dog

    One person found this helpful

  11. Franny n Frankie

    5.0 out of 5 stars

    Extremely helpful

    Great relief for our dogWorks instantly and goes on easyDefinitely would recommend this to friends

  12. Amazon Customer

    5.0 out of 5 stars

    great

    great

  13. pamangela

    5.0 out of 5 stars

    fantastic

    A must for anyone with a dog that has hot spots! works immediately!

  14. jim

    5.0 out of 5 stars

    Works

    Easy to use

    One person found this helpful

  15. bjw4148

    4.0 out of 5 stars

    Stains by Bichon Frise fur

    The product does stop the itch but stains my Bichon fur yellowish color. I like the cream better because no staining.

    3 people found this helpful

  16. Kathy

    5.0 out of 5 stars

    Great Product!

    I am pleased with this product. Zymox has a number of good products. Zymox also makes Otic Enzymatic Solution that cures dog ear infections in 24 hours. Zymox stands for quality! Their products actually do what they claim to do!!!

    3 people found this helpful

  17. Jo Renee

    5.0 out of 5 stars

    It works!

    I have to write a review for this as it really works! I would give it 10 stars if I could. I’ve bought multiple products that have done nothing, and I’m so thankful that I found this. My cat has a place on his belly that he licked a sore spot on. I spray this in my hand to warm it up a bit, then rub it on the spot. He walks around while it dries, and it must help the itching as he’s not licking anymore. I think this is day 5 and it’s mostly healed up, and no more licking it. Thank you so much as our last vet trip for this was about 1400$, and he got pancreatitis from the allergy shot they gave him.

    5 people found this helpful

  18. Jamie Dukus

    5.0 out of 5 stars

    Works great for hot spots!

    Cleared up my dogs got spots and avoided a vet visit!

    One person found this helpful

  19. stacey g

    5.0 out of 5 stars

    great price

    easy to use, always works great!

  20. Amazon Customer

    5.0 out of 5 stars

    Best Product!!

    This is the best for paw licking! Instantly stops itching on my dog’s paws and irritated areas! It’s a miracle!

  21. nancy j duggar

    5.0 out of 5 stars

    Helps itching

    Works wellI don’t understand why my previous review didn’t meet guidelines

  22. JayDee

    4.0 out of 5 stars

    Great for clearing up hives that our siamese cats get from time to time.

    The 1% hydrocortisone – as prescribed -seems to do the trick…. and rather quickly

    One person found this helpful

  23. Amazon Customer

    5.0 out of 5 stars

    Amazing!

    This stuff has been life changing for my sweet lab mix! I have tried everything under the sun for my baby and nothing worked until I found Zymox. I use it in conjunction with the Zymox LP3 Enzyme Shampoo and my boys belly is no longer red, itchy, and inflamed. He’s been on steroids from the vet, prescription allergy meds, over the counter meds, and I kid you not I have tried EVERYTHING that says it will help dogs with skin allergies. We have spent thousands at this point just trying to get him relief. After three weeks of once a week baths, this spray once in the morning and once at night, and two Benadryl and fish oil tablets with his dinner, his belly is soft and smooth and is starting to grow hair back. I never thought it would happen!

    One person found this helpful

  24. Linda

    5.0 out of 5 stars

    Amazing

    This product worked instantly, stopped my dog from itching now waiting for his hair to grow back. Can’t wait to try the shampoo .

    One person found this helpful

  25. Patricia Estilette

    5.0 out of 5 stars

    spray

    this makes a big difference for my cat, She has been having scabby sores a long time. bathing and using other medicated sprays did not do the job.

  26. K.Lee

    5.0 out of 5 stars

    Stopped Biting Paws!!!

    Sprayed this on my dogs paws and she IMMEDIATELY stopped biting them!!! Absolute winner!!!

    One person found this helpful

  27. Amazon Customer

    5.0 out of 5 stars

    Must have product that I always have on hand for my English Bulldog

    English bulldogs occasionally have skin troubles, and with one spray of this product, it is cleared up quickly before it gets worse. I like being able to be proactive, for his sake, rather than waiting to get in to see the Vet. I have used it on and in his ears, between his toes, on his paw pads, and have wiped it in his facial folds when he’s had a moist irritation. Really, anywhere he gets an occasional abrasion this works for him. It’s a must have for my baby boy because he is very active and get’s into stuff, nosing around. It’s saved time (and his suffering) by nipping those pesky little problems in the bud before having to wait hours or days to see a Vet and then spend hundreds of dollars. I can take care of it immediately, myself!

    One person found this helpful

  28. Kris JeanKris Jean

    5.0 out of 5 stars

    Hot spots gone! Lifesaver for sensation skin!

    The stuff is a lifesaver for a dog. Bruce has really severe allergies and if he eats outside of his diet he gets itchy skin and hotspots immediately. They get so bad and he gets so red all over his body that he starts to lick and bite. I included pictures in my review so you can see what he looks like. Once we see this happening we spray Xymox once a day or maybe every other day. As long as we spray the area and put a donut around his head to make sure he doesn’t bite it he normally heals within two weeks. This stuff has really saved us and you can tell that it really helps Bruce relax and probably feels good. He for sure starts running when he sees us come with the spray but it has helped him quite a bit.

    7 people found this helpful

  29. Amazon Customer

    5.0 out of 5 stars

    Good

    Works well

  30. Kimberly Munger

    5.0 out of 5 stars

    Awesome

    My dog has a skin problem and they scab in or itchy and then leave open sores. I was spending a lot of money at the vets and nothing worked. I seen this online and figured well it’s only $14 compared to the hundreds of dollars I had spent at the vets. I sprayed it on every other day which is less than it says to do and oh my gosh it took the itching away and everything healed quickly. This medicine is phenomenal I keep one to two bottles in my house.

    One person found this helpful

  31. Billy

    5.0 out of 5 stars

    Review

    Love this stuff! Works great for my dog!

    One person found this helpful

  32. Pawsjes

    5.0 out of 5 stars

    Best anti itch topical spray I ever used.

    I’ve been using zymox products for a couple of years and liked all of them. Then I saw the hot spot spray and had to buy it. I have 2 small dogs with allergy’s which makes them itch and scratch a lot especially in the summer months. This stuff works better than anything I have tried. It must be comforting to them because they like to have it applied. It’s a little expensive but they are worth it.

    One person found this helpful

  33. Sandra Dyl

    4.0 out of 5 stars

    Twice the cortisone of most sprays but the bottle is only 2 oz and is very small

    Our Labrador Retriever has a lot of allergies, and his ears, neck and elbows itch frequently. Our veterinarian had recommended another topical spray that requires a prescription, but it is no longer available. We were looking for something to give our dog some relief from the itching, and the veterinarian recommended that we look for a good cortisone spray.PROS:1. This spray has a higher amount of cortisone than most of the other sprays we looked at. It has worked the best to relieve itching of any cortisone spray other than the prescription spray we can no longer get.CONS:1. The bottle is only 2 oz, and with a large dog it may not last very long.

    3 people found this helpful

  34. Patricia C.

    5.0 out of 5 stars

    Finally something that gives my cat relief!

    This product worked beautifully on my poor itchy cat. He is finally able to relax and rest.

    One person found this helpful

  35. Z. M.

    5.0 out of 5 stars

    Miracle in a bottle!!

    This stuff is a game changer! I have a semi-feral FIV positive senior cat who lives outdoors. Despite giving him flea meds, he gets terrible flea allergies which he’ll pick at until it becomes a bacterial infection. The vet gave him a steroid shot, but shortly after I noticed he had bloody scabs ALL OVER his body. Poor thing must have been so uncomfortable. I ordered this spray due to the higher amount of hydrocortisone in it. It’s now day 8 of giving him this spray (1x daily) and his scabs are almost 100% gone!!!! And he doesn’t even fight me when I do it, probably because he knows it gives him such relief from the itch. Truly a miracle in a bottle and much cheaper and more effective than the vet.

    10 people found this helpful

  36. rose

    5.0 out of 5 stars

    Best medecine for hot spots.

    I have been using zymox products on all my Shar Pei for years and it is by far the best treatment for skin injuries and hot spots. It stops the itch and irritation and helps heal the wound.

    2 people found this helpful

  37. Anonymous

    2.0 out of 5 stars

    Didn’t help my dog

    This product did not help my poor dog. She was stil incredibly itchy and had hot spots.

  38. Hound Mum

    2.0 out of 5 stars

    Didn’t work for us

    Item didn’t work for me but may for you. Not impressed.

  39. laurilauri

    5.0 out of 5 stars

    actually works

    before and after photo of joeystar.she gets contact dermatitis from everything.she removed the hair from her belly in 2016 and hasn’t had any.since.tried everything the vet has offered including 125$ apoquel. this spray immediately calmed .

    2 people found this helpful

  40. Brenda

    5.0 out of 5 stars

    This is a great product for my dog who suffers from allergies.

    This product works very well to help heal up spots where my dog scratches and makes a sore. I put it on him and then put his e-collar on so he can’t get to the spot.

    One person found this helpful

  41. Joe Williams

    5.0 out of 5 stars

    Amazing how fast it works

    My Timmy cat has allergies and always has breakouts of bumps all over his skin. Every time I use this medicine, the bumps are completely gone by next day and Timmy is always in better mood.I highly recommend this for any fur babies that have skin bump problems. I’m amazed every time I use it and how well and fast this works.

    2 people found this helpful

  42. Joshua Azran

    5.0 out of 5 stars

    Worked when the prescription spray didn’t

    We adopted a dog from a shelter and her paws were brown, dry and very very itchy. We tried everything to help her, prescription and nonprescription, allergy shots and supplements, but nothing worked. It was a vicious cycle, as she would lick and the licking made it worse and worse, we even had to use a cone to stop her from ripping her own skin off, I was losing hope, until I came across this spray. Seriously this stuff works amazing, from first use I’ve noticed a serious change, she can finally rest without waking up all the time to lick, finally our new fur baby can sleep and not suffer anymore! Thank you for saving Bella!

    5 people found this helpful

  43. Amazon Customer

    5.0 out of 5 stars

    I wish I had known about this product sooner!

    This spray was a saving grace for my cat! She was suffering from a severe case of flea bite dermatitis. Her skin was so badly inflamed with open wounds that I couldn’t give her a flea bath as usual. I tried applying a flea spray (avoiding the affected area), and she hated it. I think the fumes irritated her eyes and nose. She was so upset and obsessive that she wouldn’t stop licking the affected area, so I put a cone collar on her, which made it hard for her to eat and drink. This spray saved her skin and mental health! After the first application, she immediately calmed down and took a long nap. Applying the spray just once a day was enough to soothe her skin and stop her obsessive licking. And her skin healed very quickly. If I had known about this product sooner, it would’ve saved a lot of pain and heartache. I highly recommend it!

    6 people found this helpful

  44. Wendy Kramer

    5.0 out of 5 stars

    Dog tested

    This product worked well on our Ridgeback who are infamous for itchy infectious skin spots. This product cleared up his issues straight away.

  45. Oklahoma buyer

    5.0 out of 5 stars

    The best.

    I started using this for my dogs scraps, irritations, rashes and it works fast and heals quick within days & no funny order. Doesn’t bother my dogs and even acts like a skin/fur conditioner. And you don’t need a lot to work.

    2 people found this helpful

  46. gretchen tate

    3.0 out of 5 stars

    Leaky

    The Zymox did help my kitty’s ears. He finally has wanted ear rubs and he’s not scratching them.However, the packaging was subpar but I wanted the ire, for his ears. I ended up putting the bottle in a zip lock bag for the leaking. If it didn’t leak I would’ve given a 5 star

  47. Sondra Soundly

    5.0 out of 5 stars

    This product works!

    An outdoor planter had very tiny white insects on its leaves. One spray and all seems well.

  48. Kimberly C

    5.0 out of 5 stars

    Miracle spray

    I have been using this brand for years! So happy it’s still great within a couple days redness irritation itching gone and I have frenchies they’re allergic to everything this helps so much with spring time paws saves me many trips to the vet.

    3 people found this helpful

  49. Terrence Olson Jr.

    4.0 out of 5 stars

    Great spray

    Works well on the dogs hot spot, he’s licked through other brands but not this one

    One person found this helpful

  50. madameleota

    2.0 out of 5 stars

    Left orangish stains on my dog’s fur

    Useless. Created a big mess.

  51. T-usea

    5.0 out of 5 stars

    It’s work for my dog!!

    I have 3 dogs, one of my oldest had seasonal allergies, constantly chewing his toe and paws. Some paws break and bleeding. I’m professional dog groomer. Extremely careful their food, groom them every week. But nothing help his chewing issues. Especially when he goes to back yard and get sand( I’m in FL ground soils almost sand) starts chewing horribly. I got this spray and instantly notice about decreasing his chew. Skin was red and bleeding but only one day, skin break stopped and no more blood on his toe. Still he chews sometimes but definitely works!! I spray 2 times day, after take him backyard.

    2 people found this helpful

  52. Rescue Dogs

    5.0 out of 5 stars

    Relief for inflamed allergy skin

    My dog has been diagnosed with dust mite, storage mite, grass, tree, & shrub allergies. Lucky me! $2K later – this spray has worked better than any topical the vet derm has given me. I spray this (one spray) inside my dogs ear flaps & between his toes when his skin looks extremely inflamed. Within an hour, the red-purple inflammation is completely gone. I have to think it is providing great relief – based on the quick change in color of his skin. I bought the cream version of this – and it didn’t work nearly as well as this spray. Not sure why. I find all the Xymox products to be extremely good. The ear (gel) Xymox Otic (with hydrocortisone) is also awesome for inflamed, infected ears.

    33 people found this helpful

  53. Barbara Etchevarne

    5.0 out of 5 stars

    Works wonderfully

    My almost two year old pitbull developed yeast in her paws, and it was even going down her nails and in between her toes. I had tried a few different home remedies, and even went to the vet, but not even the medication worked. I bought this spray (had to buy it 3 times) and it’s slowly been going away. I’ve been applying it nightly right before she goes to bed. The ONLY complaint I have is that the bottle is only 2 ounces. This stuff goes FAST. Especially when you have a pup with big paws. I just wish they’d make larger bottles. In a matter of a month, I’ve purchased 3 bottles.

    6 people found this helpful

  54. JAGutz

    5.0 out of 5 stars

    It works!

    Like all Zymox products I’ve used, it works exactly as expected. My only complaint, and it’s super minor for us, it that it stains my dog’s white fur a yellow tinge. It immediately calms his inflamed skin and hot spots.

    4 people found this helpful

  55. Rhonda Bohlen

    5.0 out of 5 stars

    Great

    Works great!!

  56. GG

    5.0 out of 5 stars

    Great product for my fur baby and his allergies

    Feel safe using this product!

  57. m-chan

    5.0 out of 5 stars

    Excellent in Many Ways!

    For several years now, I’ve used Zymox whenever my cat has developed “hot spots” and begun to overlick the spot, making it raw. It works perfectly for that. At the moment, my cat is having a problem with kitty acne under his chin, which he tends to scratch at and make bleed, and the Zymox is helping with that too. (I don’t spray it on there, but use a cotton round for application.)This is just plain good stuff, and if you have a cat, I recommend you keep a bottle on hand.

    3 people found this helpful

  58. kitty

    4.0 out of 5 stars

    Seems to be working

    I bought this to help my cat who has severe flea allergies, after 5 days it seems to be helping. Thank you. Four stars only because I have just started using it.

    One person found this helpful

  59. Nancy Hancock

    4.0 out of 5 stars

    Easy to apply worked

    Hot spots and skin irritation worked well and quickly

    One person found this helpful

  60. Amazon Customer

    5.0 out of 5 stars

    Awesome

    This product help bring isn’t relief to my dog’s itch

    One person found this helpful

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